个人简介

2012年9月进入南京医科大学儿科学硕博连读，师从张爱华教授，期间参与多项国家自然科学基金，并独立主持校级创新课题，培养了研究能力与科研创新精神。2016年7月进入南京医科大学附属儿童医院重点实验室专职从事科研工作，并于2017年9月进入南京医科大学临床医学博士后流动站，合作导师为胡志斌教授和贾占军教授。工作期间以第一作者在Kidney International（IF：8.3）、Am J Physiol Renal Physiol（IF：3.3）等杂志发表SCI论文多篇，是Frontiers Physiology、Plos one、Scientific reports 等SCI期刊审稿专家。

主持科研项目

1.Lonp1：足细胞损伤干预的新靶标（JQX18007），南京市科技发展杰出青年项目，2019.1-2021.12，50万

2.Lonp1在足细胞损伤中的作用及机制研究（2018M632341），中国博士后基金面上项目，2018.6-2020.6，5万

3.MUTYH在急性肾小管损伤中的作用及机制研究（81700595），国家自然科学基金青年科学基金，2018.01-2020.12，20 万

代表性论文

1.Bai M#, Chen H#, Ding D, Song R, Lin J, Zhang Y, Guo Y, Chen S, Ding G, Zhang Y, Jia Z, Huang S, He JC, Yang L, Zhang A*. MicroRNA-214 promotes chronic kidney disease by disrupting mitochondrial oxidative phosphorylation. Kidney Int. 2019 Jun;95(6):1389-1404. 

2.Mi Bai#, Luan Lei#, Shuqin Wang, Dan Ding, Xiaowen Yu, Yan Guo, Shuang Chen, Yang Du, Deyi Li, Yue Zhang, Songming Huang, Zhanjun Jia*, Aihua Zhang*. BMP1 inhibitor UK-383,367 attenuates renal fibrosis and inflammation in CKD, Am J Physiol Renal Physiol, 2019, 317(6): 1430-1438.

3.Zhao M#, Bai M#, Ding G, Zhang Y, Huang S, Jia Z, Zhang A.*Angiotensin II Stimulates the NLRP3 Inflammasome to Induce Podocyte Injury and Mitochondrial Dysfunction. Kidney Dis (Basel). 2018 Jun;4(2):83-94. 

4.Bai Mi#, Chen Ying#, Zhao Min, Zhang Yue, He John Ci-Jiang, Huang Songming, Jia Zhanjun*, Zhang Aihua, NLRP3 Inflammasome Activation Contributes to Aldosterone-induced Podocyte Injury, Am J Physiol Renal Physiol, 2017 Apr 1;312(4):F556-F564. 

5.ai Mi#, Che Ruochen#, Zhang Yue, Yuan Yanggang, Zhu Chunhua, Ding Guixia, Jia Zhanjun, Huang Songming, Zhang Aihua*, Reactive Oxygen Species-Initiated Autophagy Opposes Aldosterone-Induced Podocyte Injury, Am J Physiol Renal Physiol, 2016, 310:669-678.  

6.Guo Y#, Ni J#, Chen S, Bai M, Lin J, Ding G, Zhang Y, Sun P, Jia Z, Huang S, Yang L, Zhang A*. MicroRNA-709 Mediates Acute Tubular Injury through Effects on Mitochondrial Function. J Am Soc Nephrol. 2018 Feb;29(2):449-461.

7.Guo Y#, Deng X#, Chen S, Yang L, Ni J, Wang R, Lin J, Bai M, Jia Z, Huang S, Zhang A*. MicroRNA-30e targets BNIP3L to protect against aldosterone-induced podocyte apoptosis and mitochondrial dysfunction. Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F589-F598. 

8.Zhao M, Yuan Y, Bai M, Ding G, Jia Z, Huang S, Zhang A*.PGC-1α overexpression protects against aldosterone-induced podocyte depletion: role of mitochondria. Oncotarget. 2016 Mar 15;7(11):12150-12562.

9.Che R, Zhu C, Ding G, Zhao M, Bai M, Jia Z, Zhang A, Huang S*. Huaier Cream Protects against Adriamycin-Induced Nephropathy by Restoring Mitochondrial Function via PGC-1α Upregulation. PPAR Res. 2015;2015:720383. 

10.Zhuang Yibo, Ding Guixia, Zhao Min, Bai Mi, Yang Lingyun, Ni Jiajia, Wang Rong, Jia Zhanjun, Huang Songming, Zhang Aihua*, NLRP3 inflammasome mediates albumin-induced renal tubular injury through impaired mitochondrial function, J Biol Chem. 2014, 289(36):25101-25111. 

授权专利

1.实用新型专利：一种通过检测尿液miR-214来预测肾脏纤维化程度的试剂盒。专利号：ZL201821108928.1，授权日：bet36体育在线：7月19日。发明人：张爱华，白咪，贾占军，张玥，黄松明，郭燕，陈爽，杜阳